We deliver error-free, PTO-compliant sequence listings with fast turnaround, competitive pricing, and expert precision – ensuring your patent applications avoid delays and rejections.







Similar patents may be filed while compliance hurdles persist.

Rejections extend timelines and escalate expenses.

In-house attempts often require multiple amendments, wasting time.

Errors may narrow patent claims, weakening protection.

Prolonged time-to-market reduces competitive advantage.
Handle sequence data extraction, formatting, and validation.
Perfectly formatted listings ready in 1-2 days.
Focus on innovation while we ensure compliance.
Proprietary tools catch errors standard methods miss.
At our Sequence Listing Company, we specialize exclusively in creating perfect patent sequence listings for biotechnology and pharmaceutical companies. Founded by patent attorneys and bioinformatics specialists with over 10 years of experience, we understand the critical intersection of scientific innovation and intellectual property protection. Our dedicated team has helped hundreds of companies successfully navigate the complex regulatory requirements of sequence listings across global patent offices. We combine technical precision with regulatory expertise to ensure your valuable innovations receive the protection they deserve without delays or complications.
Individual Inventor – Genetic Tools Developer
Nigeria
Effectual Services (TheSequenceListing.com) was referred to me by a colleague, and they did not fail. They formatted my DNA sequences to the proper style and even liaised with my IP agent overseas. As a solo innovator, I greatly appreciated their transparency and assistance.
Multinational Pharma Company
USA
We had over 200 sequences to submit, and the job was overwhelming. Effectual (TheSequenceListing.com) streamlined the entire process by a systematic, error-free procedure. They collaborated seamlessly with our in-house personnel and ensured the sequence listing met all USPTO guidelines. They are currently our first choice for future filings.
University Tech Transfer Office
UK
Effectual Services (TheSequenceListing.com) provided detailed instructions on how to transform our gene data into ST.26 format. Being a university group with little hands-on experience in sequence listings, their assistance made a significant impact in our patent application being in order the first time around.
Animal Genetics Firm
Brazil
Effectual (TheSequenceListing.com) assisted us in assembling and organizing dozens of sequences across several species for a patent application worldwide. Their organism assignments and annotations were perfect. We required no revision. Great work!
The World Intellectual Property Organization (WIPO) sequence listing requirements represent a critical component of international patent applications in biotechnology and life sciences.
In the expanding field of pharmaceutical and biotechnology innovation, the proper and standardized publication of nucleotide and amino acid sequences is essential in the securing of intellectual property rights.
A sequence listing is a document that is used to provide the nucleotide and amino acid sequences that are disclosed in a patent application. It is the part of the description of the patent application. The sequence listing contains annotations that tell about the sequence and they are the equivalence to the WIPO standard for the relevant part (ST.25 or ST.26). It is a means for an invention’s sequence data to be searchable within an IP office and in publicly available databases (e.g., INSDC databases).
They make sure that there is consistency in the way biological sequences are disclosed in patent applications all over the world, thus making it easier for the examination to be carried out and enabling the efficient electronic data exchange between patent offices.
A sequence listing must be given if you have a patent application where you have disclosed one or more nucleotide or amino acid sequences that are included in the definition of sequence disclosure according to the rules that are in force.
ST.26 is the contemporary international specification for carrying out sequence listing in an XML format. It supersedes the are ST.25 standard. The last date it is allowed for the international applications to be filed without the use of ST.26 is July 1, 2022.
ST.26 is different from the ST.25 standard in that it makes use of XML instead of plain text. The inclusion of D-amino acids, the branched sequence part, and nucleotide analogs is also required. Besides, it gives room for elaborated annotations through the feature keys and the qualifiers, it also forbids the shorter sequences (less than 10 nucleotides or 4 amino acids) which were allowed in ST.25.
Yes, ST.26 is required for every international patent application (PCT) that was filed on or after July 1, 2022 and in accordance with this, many national/regional applications are also subject to local implementation.
Effectual Services is an award-winning Intellectual Property (IP) management advisory & Consulting firm.